The Digest’s 2024 Multi-Slide Guide to Bacillus as an industrial host for the microbial production of biopolymers

Development of Bacillus as an industrial host for the microbial production of biopolymers is of industrial interest from lignocellulosic hydrolysates. In this project, researchers worked to apply ZymoChem’s Carbon Conservation (C2) technology in non-model organisms to maximize carbon efficiencies to biopolymers via minimizing loss of CO2 from lignocellulosic hydrolysates. The team applied – ABF’s state of the art metabolic engineering tools/strategies to engineer strains with improved titer and rate, metrics by >4x over base case performance. Thomas Mand, Program Manager of the Agile BioFoundry and Harshal Chokhawala, CEO, ZymoChem presented these slides at DOE Project Peer Review.